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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS1
All Species:
31.21
Human Site:
T735
Identified Species:
49.05
UniProt:
O95835
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95835
NP_004681.1
1130
126870
T735
K
A
L
Y
A
T
K
T
L
R
K
K
D
V
L
Chimpanzee
Pan troglodytes
XP_001173355
1130
126853
T735
K
A
L
Y
A
T
K
T
L
R
K
K
D
V
L
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
S475
R
D
E
E
K
R
E
S
R
I
K
S
Y
S
P
Dog
Lupus familis
XP_534537
1097
121903
V722
N
R
N
Q
V
A
H
V
K
A
E
R
D
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR2
1129
126167
T734
K
A
L
Y
A
T
K
T
L
R
K
K
D
V
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
T725
D
A
L
Y
A
T
K
T
L
R
K
K
D
V
L
Chicken
Gallus gallus
XP_419666
1136
127431
T741
K
A
L
Y
A
T
K
T
L
R
K
K
D
V
L
Frog
Xenopus laevis
NP_001087838
1118
125984
T721
N
A
L
Y
A
M
K
T
L
R
K
K
D
V
L
Zebra Danio
Brachydanio rerio
NP_001018346
1068
120780
S711
W
V
V
R
L
Y
Y
S
F
Q
D
K
D
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA38
1105
122470
T750
N
H
L
Y
A
M
K
T
L
R
K
A
D
V
L
Honey Bee
Apis mellifera
XP_395146
1137
124999
T771
N
Q
F
Y
A
M
K
T
L
R
K
A
D
V
L
Nematode Worm
Caenorhab. elegans
Q2L6W9
476
55529
A142
E
R
D
I
L
S
E
A
D
C
D
W
V
V
K
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
K811
N
A
L
Y
A
V
K
K
L
R
K
L
D
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
A422
L
Y
Y
S
F
Q
D
A
Q
Y
L
Y
L
I
M
Red Bread Mold
Neurospora crassa
P38679
598
67999
D264
A
H
V
R
A
E
R
D
I
L
A
E
S
D
S
Conservation
Percent
Protein Identity:
100
99.6
35.8
50.9
N.A.
92.8
N.A.
N.A.
80.8
85.2
74.7
63.1
N.A.
38.6
40.2
20.7
38
Protein Similarity:
100
99.8
44.7
63.4
N.A.
96.7
N.A.
N.A.
87.1
92.1
83.4
73.7
N.A.
50.2
52.6
29.6
51.9
P-Site Identity:
100
100
6.6
13.3
N.A.
100
N.A.
N.A.
93.3
100
86.6
20
N.A.
73.3
66.6
6.6
66.6
P-Site Similarity:
100
100
26.6
33.3
N.A.
100
N.A.
N.A.
93.3
100
86.6
40
N.A.
73.3
66.6
26.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
24.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
47
0
0
67
7
0
14
0
7
7
14
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
7
7
7
0
0
0
7
7
7
0
14
0
74
7
0
% D
% Glu:
7
0
7
7
0
7
14
0
0
0
7
7
0
0
0
% E
% Phe:
0
0
7
0
7
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
14
0
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
7
7
0
0
0
14
7
% I
% Lys:
27
0
0
0
7
0
60
7
7
0
67
47
0
0
7
% K
% Leu:
7
0
54
0
14
0
0
0
60
7
7
7
7
0
67
% L
% Met:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
7
% M
% Asn:
34
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
7
0
7
0
7
0
0
7
7
0
0
0
0
0
% Q
% Arg:
7
14
0
14
0
7
7
0
7
60
0
7
0
0
0
% R
% Ser:
0
0
0
7
0
7
0
14
0
0
0
7
7
7
7
% S
% Thr:
0
0
0
0
0
34
0
54
0
0
0
0
0
0
0
% T
% Val:
0
7
14
0
7
7
0
7
0
0
0
0
7
67
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
7
7
60
0
7
7
0
0
7
0
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _